History of Paracetamol:
“Paracetamol” — People who haven't heard of this object may not be able to find. Let's find out the birth story of this everyday companion called Paracetamol.
The time will be around 1836. One night, Anna, the wife of the Spanish King Luis Jeremy nu Fernandez DE Capri o, developed a high fever.
Tertiary (malaria) fever. There is no peace in the king's mind, no sleep in his eyes. Dear queen bedridden- I don, 't feel like doing anything! All the doctors of the state was called. No one could solve it. Vaidya-Kabiraj (Doctors of that times) was called from far and wide.
Everyone disappointed the king. Meanwhile, the condition of the queen goes on. The queen is not going to be healed at all. The king can't think with one eye. This went on for a few more days.
One spring afternoon, the king was sitting in the garden with his face covered. The gentle breeze and the smell of sweet tulips could not keep the king's mind cheerful. Suddenly the guard came to the king with a letter wrapped in a colorful envelope. The then governor of Lu xor wrote a letter to the king.
One spring afternoon, the king was sitting in the garden with his face covered. The gentle breeze and the smell of sweet tulips could not keep the king's mind cheerful. Suddenly the guard came to the king with a letter wrapped in a colorful envelope. The then governor of Lu xor wrote a letter to the king.
In the letter, he advised the queen to use the bark of the cinchona tree. He mentioned that the bark of this tree works to cure fever.
This was a landmark letter. Whose witness we are now. Hundreds of patients are recovering by taking paracetamol every day. In the ward or in the chamber — we prescribe this medicine all the time. However, after reading the letter, the king was relieved and finally the queen recovered. From then on, the use of Cinchona plant as Anti-Pyratic began.
But disaster struck in 180' (ca. 55 m)s. This great cinchona tree got lost due to widespread use. People started looking for alternative ways. Acetanilide was discovered in 18 and Phenacetin in 18.
Interestingly, Sir Hormone has already developed a drug called paracetamol from Northrop Morse p-Nitrophenol, although his invention was not accepted by medical science at the time. Another interesting piece of information came out in 1899. ‘Paracetamol’ is found as Metabolites in the urine of Acetanilide users.
A conference was organized by The Institute for the Study of Analgesic and Sedative Drugs in New York,1947. Scientists Bernard and Julius were tasked with finding out why non-aspirin agents potentially develop lethal and methemoglobinemia.
A conference was organized by The Institute for the Study of Analgesic and Sedative Drugs in New York,1947. Scientists Bernard and Julius were tasked with finding out why non-aspirin agents potentially develop lethal and methemoglobinemia.
In 1948, they discovered that the main reason behind the action of acetanilide as an antipyretic is its metabolites, “paracetamol.” Therefore, if you use an only paracetamol without using acetanilide, there will be no complications.
Since then, paracetamol has been used instead of acetanilide It was later introduced commercially in the United States in 1955 and in the United Kingdom in 1956.
The journey of paracetamol has been going on since then.
The journey of paracetamol has been going on since then.
Conclusion:
Paracetamol is a drug of everyday's usage. This is a very common drug and i bet will be found commonly in every house country wide. So here i told you the amazing hisyory of Paracetamol - an excellent journey towards mankind.
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